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Anticancer drugs of tomorrow: apoptotic pathways as targets for drug design

✍ Scribed by Marek Los; Christof J Burek; Christopher Stroh; Konrad Benedyk; Hubert Hug; Andrzej Mackiewicz


Book ID
114384243
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
137 KB
Volume
8
Category
Article
ISSN
1359-6446

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The currently understood function for Ras in signal transduction is in mediating the transmission of signals from external growth factors to the cell nucleus. Mutated forms of this GTP-binding protein are found in 30% of human cancers with particularly high prevalence in colon and pancreatic carcino