✦ LIBER ✦

Bcl-2 family proteins as targets for anticancer drug design

✍ Scribed by Huang, Ziwei

Book ID: 110064392
Publisher: Nature Publishing Group
Year: 2000
Tongue: English
Weight: 178 KB
Volume: 19
Category: Article
ISSN: 0950-9232
DOI: 10.1038/sj.onc.1204087

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Farnesyltransferase as a target for anti

Farnesyltransferase as a target for anticancer drug design

✍ Yimin Qian; Saïd M. Sebti; Andrew D. Hamilton 📂 Article 📅 1997 🏛 Wiley (John Wiley & Sons) 🌐 English ⚖ 233 KB 👁 2 views

The currently understood function for Ras in signal transduction is in mediating the transmission of signals from external growth factors to the cell nucleus. Mutated forms of this GTP-binding protein are found in 30% of human cancers with particularly high prevalence in colon and pancreatic carcino

Targeting BCL-2 family proteins to overc

Targeting BCL-2 family proteins to overcome drug resistance in non-small cell lung cancer

✍ Emmanuelle Wesarg; Sandra Hoffarth; Rainer Wiewrodt; Monika Kröll; Stefan Bieste 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 French ⚖ 422 KB

## Abstract Cytotoxic chemotherapies are standard of care for patients suffering from advanced non‐small cell lung cancer (NSCLC). However, objective responses are only achieved in 20% of cases and long‐term survival is rarely observed. Clinically applied anticancer drugs exert at least some of the

Recent advances in the development of an

Recent advances in the development of anticancer agents targeting cell death inhibitors in the Bcl-2 protein family

✍ Shangary, S; Johnson, D E 📂 Article 📅 2003 🏛 Nature Publishing Group 🌐 English ⚖ 212 KB

DNA G-Quadruplexes, Telomere-Specific Pr

DNA G-Quadruplexes, Telomere-Specific Proteins and Telomere-Associated Enzymes as Potential Targets for New Anticancer Drugs

✍ Eric Raymond; Jean-Charles Soria; Elzbieta lzbicka; Francois Boussin; Laurence H 📂 Article 📅 2000 🏛 Springer US 🌐 English ⚖ 156 KB

Immunohistochemical Study for the Expres

Immunohistochemical Study for the Expression of Bcl-2 Family Proteins in Walker 256 Carcinosarcoma Cells under the Influence of Cytostatic Drugs

✍ E. V. Ovsjanko; E. L. Lushnikova; P. M. Larionov; S. A. Arkhipov; L. M. Nepomnya 📂 Article 📅 2009 🏛 Springer US 🌐 English ⚖ 594 KB

Mn-SOD antisense upregulates in vivo apo

Mn-SOD antisense upregulates in vivo apoptosis of squamous cell carcinoma cells by anticancer drugs and γ-rays regulating expression of the BCL-2 family proteins, COX-2 and p21

✍ Eisaku Ueta; Kazunori Yoneda; Tsuyoshi Kimura; Yukihiro Tatemoto; Sayoko Doi; Te 📂 Article 📅 2001 🏛 John Wiley and Sons 🌐 French ⚖ 388 KB 👁 2 views

ROIs and their scavengers are associated with apoptosis induction by anticancer drugs and ␥-rays, but the details have not been clarified. We examined the effect of transfection of Mn-SOD antisense on apoptosis by 5-FU, PLM, CDDP and ␥-rays using nu/nu mice. After inoculation of Mn-SOD antisense-tra