Antibody activity associated with immunoglobulins synthesised by human lymphoblastoid cell lines
β Scribed by STEEL, C. M.; EVANS, JUDITH; JOSS, A. W. L.; ARTHUR, ELIZABETH
- Book ID
- 109693752
- Publisher
- Nature Publishing Group
- Year
- 1974
- Tongue
- English
- Weight
- 360 KB
- Volume
- 252
- Category
- Article
- ISSN
- 0028-0836
- DOI
- 10.1038/252604a0
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Tumorigenicity of human lymphoma and lymphoblastoid &ell lines was assessed by their ability to form growing and transplantable masses on subcutaneous inoculation into neonatally thymectomized, Ara-C-protected, totalbody-irradiated mice. By these criteria, I 2 lines of known malignant origin were tu
## Abstract A population of nonβspecific effector lymphocytes is generated in response to stimulation with lymphoblastoid cell lines (LCL). These cytotoxic cells have an activity analogous to that exhibited by natural killer (NK) cells. When lymphoid cell lines established by transformation with Ep