The results presented provide evidence that the HLA specificity known as MT3, BR4, or Hon7 can serve as a restriction epitope for the proliferation of certain T cells responding to mumps viral antigen. This restriction determinant was found to be HLA-linked in family studies, and to segregate centro
✦ LIBER ✦
Human lymphoblastoid cell lines secreting antibodies with restricted HLA specificity
✍ Scribed by M. P. Pistillo; N. Tanigaki; O. Mazzoleni; E. Ciccone; U. Hämmerling; M. Park; P I. Terasaki; G. B. Ferrara
- Book ID
- 104731856
- Publisher
- Springer-Verlag
- Year
- 1987
- Tongue
- English
- Weight
- 615 KB
- Volume
- 25
- Category
- Article
- ISSN
- 0093-7711
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## Abstract The cytotoxic response of human lymphocytes to the autologous lymphoblastoid cell line (LCL) was investigated with five Epstein‐Barr virus (EBV)‐seropositive and four seronegative donors and an additional donor who seroconverted during the course of the study. LCL stimulation was carrie