Antibodies to insulin
โ Scribed by R. Cobb; T. Hanley; I. L. S. Mitchell; G. Howard Smith
- Book ID
- 104769389
- Publisher
- Springer
- Year
- 1966
- Tongue
- English
- Weight
- 122 KB
- Volume
- 2
- Category
- Article
- ISSN
- 0012-186X
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
We immunized mice with insulin and found that those strains that develop insulin antibodies subsequently produce insulin-like activity in amount equivalent to 300-400 ng insulin per ml serum. The activity was due exclusively to IgG2 antibodies. Bioactivity could be blocked efficiently by insulin an
In the presence of anti-insulin antibody, 2-to 3-fold enhancement of 1251-insulin binding to liver membranes was observed when binding was estimated by the radioactivity of 125I-insulin bound to the membrane pellets. However, after 125I-insulin was covalently cross-linked to liver membranes using di