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Antibodies to a 35KDa nerve glycoprotein in serum of patients with motor neuron disease

โœ Scribed by E. Noblle-Grazio; E. Manfredini; G. Spagnol; G. Scarlato


Book ID
119108142
Publisher
Elsevier Science
Year
1991
Tongue
English
Weight
70 KB
Volume
35
Category
Article
ISSN
0165-5728

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Antibodies to GM1 and GD1b in patients w
โœ Dr. Michael E. Shy; Vance A. Evans; Fred D. Lublin; Robert L. Knobler; Terry Hei ๐Ÿ“‚ Article ๐Ÿ“… 1989 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 464 KB ๐Ÿ‘ 2 views

Fifty-nine percent of 49 patients with motor neuron disease and 25% of 91 control subjects had IgM antibodies to ganglioside GM1 but usually not to GDlb at titers less than 1:80. This suggests that antibodies to GM1 may be part of the normal human antibody repertoire. However, given the higher incid