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Serum anti-GM1 and anti-GD1a antibodies in patients with motor neuron disease

✍ Scribed by C. Voumvourakis; A. Rombos; M. M. Konstantoulakis; I. Segditsa; C. Papageorgiou


Book ID
114783777
Publisher
John Wiley and Sons
Year
1992
Tongue
English
Weight
491 KB
Volume
86
Category
Article
ISSN
0001-6314

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Antibodies to GM1 and GD1b in patients w
✍ Dr. Michael E. Shy; Vance A. Evans; Fred D. Lublin; Robert L. Knobler; Terry Hei πŸ“‚ Article πŸ“… 1989 πŸ› John Wiley and Sons 🌐 English βš– 464 KB πŸ‘ 2 views

Fifty-nine percent of 49 patients with motor neuron disease and 25% of 91 control subjects had IgM antibodies to ganglioside GM1 but usually not to GDlb at titers less than 1:80. This suggests that antibodies to GM1 may be part of the normal human antibody repertoire. However, given the higher incid