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Antibodies recognizing cholinergic neurons and thyroglobuline are found in the cerebrospinal fluid of a subgroup of patients with Alzheimer's disease

✍ Scribed by Amanda McRae-Degueurce; Kenneth Haglid; Lars Rosengren; Anders Wallin; Kaj Blennow; C.-G. Gottfries; Prof. Annica Dahlström


Publisher
John Wiley and Sons
Year
1988
Tongue
English
Weight
763 KB
Volume
15
Category
Article
ISSN
0272-4391

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Evidence for the presence of antibodies
✍ P. Foley; H. F. Bradford; M. Docherty; H. Fillit; V. N. Luine; B. McEwen; G. Buc 📂 Article 📅 1988 🏛 Springer 🌐 English ⚖ 638 KB

A blind study showing that serum from patients with Alzheimer's disease causes immunolysis of mammalian brain synaptosomes is reported. Control, aged-matched, sera were largely without effect. The immunolysis was directed mainly against cholinergic synaptosomes. The data presented support the hypoth