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Inhibition of acetyl- and butyryl-cholinesterase in the cerebrospinal fluid of patients with Alzheimer's disease by rivastigmine: correlation with cognitive benefit

✍ Scribed by E. Giacobini; R. Spiegel; A. Enz; A. E. Veroff; N. R. Cutler


Publisher
Springer
Year
2002
Tongue
English
Weight
169 KB
Volume
109
Category
Article
ISSN
1435-1463

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## Abstract To investigate the possible role of oxidative RNA damage in the pathogenesis of Alzheimer's disease (AD), the concentrations of the oxidative stress marker 8‐hydroxyguanosine (8‐OHG) were measured in the cerebrospinal fluid (CSF) and the serum of patients with AD and control subjects. T