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Antibacterial and antimalarial properties of peptides that are cecropin-melittin hybrids

✍ Scribed by H.G. Boman; D. Wade; I.A. Boman; B. Wåhlin; R.B. Merrifield


Book ID
115922567
Publisher
Elsevier Science
Year
1989
Tongue
English
Weight
421 KB
Volume
259
Category
Article
ISSN
0014-5793

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Hydrophobic Effects on Antibacterial and
✍ Padmaja Juvvadi; Satyanarayana Vunnam; Elizabeth L. Merrifield; Hans G. Boman; R 📂 Article 📅 1996 🏛 John Wiley and Sons 🌐 English ⚖ 927 KB

The design of cecropin-melittin hybrid analogues is of interest due to the similarities in the structure of the antimicrobial peptides cecropin and melittin but differences in their lytic properties. We suspected that a hydrophobic residue in position 2 of milittin (Ile8 in the hybrid) plays an impo