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Antibacterial Activity of Acyclic Decapeptide Analogs of Gramicidin S

โœ Scribed by Erlanger, B. F.; Goode, L.


Book ID
121165750
Publisher
American Association for the Advancement of Science
Year
1960
Tongue
English
Weight
379 KB
Volume
131
Category
Article
ISSN
0036-8075

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Syntheses of antibacterial peptides, gra
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In order to clarify the relationship between antimicrobial activity and peptide-structure, gramicidin S analogs and cationic a-helical model peptides were designed and synthesized. Introduction of cationic side chains in hydrophilic side of gramicidin S increased antimicrobial activity against Gram-