𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Anti-sclerostin antibodies: Utility in treatment of osteoporosis

✍ Scribed by Clarke, Bart L.

Book ID
122207846
Publisher
Elsevier Science
Year
2014
Tongue
English
Weight
475 KB
Volume
78
Category
Article
ISSN
0378-5122

No coin nor oath required. For personal study only.

πŸ“œ SIMILAR VOLUMES

Sclerostin antibody treatment enhances m
Sclerostin antibody treatment enhances metaphyseal bone healing in rats
✍ Fredrik Agholme; Xiaodong Li; Hanna Isaksson; Hua Zhu Ke; Per Aspenberg πŸ“‚ Article πŸ“… 2010 πŸ› American Society for Bone and Mineral Research 🌐 English βš– 284 KB

## Abstract Sclerostin is the product of the __SOST__ gene. Loss‐of‐function mutations in the __SOST__ gene result in a high‐bone‐mass phenotype, demonstrating that sclerostin is a negative regulator of bone mass. Primarily expressed by osteocytes in bone, sclerostin is reported to bind the LRP5/6