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Anti-inflammatory effect of jeongshintang through suppression of p38 activation in human astrocytoma, U373MG cells

✍ Scribed by S.J. Kim; H.J. Jeong; B.K. Kim; N.H. Kim; J.S. Kim; K.S. Choi; H.J. Lee; S.T. Kang; S.S. Shin; W.I. Kim; H.S. Eom; K.M. Lee; J.Y. Um; S.H. Hong; H.M. Kim


Book ID
113956433
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
274 KB
Volume
81
Category
Article
ISSN
0014-4800

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Variations in intracellular free calcium concentration (A1Cazfli) were measured in intact and isolated human astrocytoma cells (U373 MG) loaded with fura-2 acetoxymethylester. Microperfusion of 50 nM substance P (SP), applied for 1 s, increased [Ca" ' Ii by 351 nM from a stable basal level of [Ca2+l