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Anti-enterovirus activity and structure–activity relationship of a series of 2,6-dihalophenyl-substituted 1H,3H-thiazolo[3,4-a]benzimidazoles

✍ Scribed by Armando M. De Palma; Ward Heggermont; Pieter Leyssen; Gerhard Pürstinger; Eva Wimmer; Erik De Clercq; Angela Rao; Anna-Maria Monforte; Alba Chimirri; Johan Neyts

Book ID: 116294130
Publisher: Elsevier Science
Year: 2007
Tongue: English
Weight: 135 KB
Volume: 353
Category: Article
ISSN: 0006-291X
DOI: 10.1016/j.bbrc.2006.12.063

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## Abstract magnified image 2‐(4‐Substituted aryl)‐4H‐[1,3]thiazolo[3,2‐a][1,3,5]triazine‐4‐thiones (**3a**, **3b**) and 2‐(2‐thiophene)‐4H‐[1,3]thiazolo[3,2‐a][1,3,5]triazine‐4‐thione (**3d**) were synthesized by the reaction of arylisothiocyanates/thiophene‐2‐isothiocyanate with 2‐aminothiazole