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Anti-CD3 antibodies for type 1 diabetes: beyond expectations

✍ Scribed by Jean-François Bach

Book ID
117308814
Publisher
The Lancet
Year
2011
Tongue
English
Weight
256 KB
Volume
378
Category
Article
ISSN
0140-6736

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## Abstract The use of anti‐CD3 monoclonal antibodies (mAbs) has moved from the bench to the bedside. The experience with the anti‐human CD3 mAb OKT3 for treatment of transplant rejection identified limitations that were largely overcome with the creation of humanized non‐FcR binding antibodies: Te