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Treatment of type 1 diabetes with anti-CD3 monoclonal antibody

✍ Scribed by Kaven C. Herold; Lesley Taylor


Book ID
111639207
Publisher
Springer-Verlag
Year
2003
Tongue
English
Weight
113 KB
Volume
28
Category
Article
ISSN
0257-277X

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Anti-CD3 mAbs for treatment of type 1 di
✍ Adam Kaufman; Kevan C. Herold πŸ“‚ Article πŸ“… 2009 πŸ› John Wiley and Sons 🌐 English βš– 86 KB

## Abstract The use of anti‐CD3 monoclonal antibodies (mAbs) has moved from the bench to the bedside. The experience with the anti‐human CD3 mAb OKT3 for treatment of transplant rejection identified limitations that were largely overcome with the creation of humanized non‐FcR binding antibodies: Te