## Abstract Nasopharyngeal carcinoma (NPC) is a rare malignancy with unique genetic, viral and environmental characteristic that distinguishes it from other head and neck carcinomas. The clinical management of NPC remains challenging largely due to the lack of early detection strategies for this tu
Anti-angiogenic and tumor-suppressive roles of candidate tumor-suppressor gene, Fibulin-2, in nasopharyngeal carcinoma
โ Scribed by Law, E W L; Cheung, A K L; Kashuba, V I; Pavlova, T V; Zabarovsky, E R; Lung, H L; Cheng, Y; Chua, D; Lai-wan Kwong, D; Tsao, S W; Sasaki, T; Stanbridge, E J; Lung, M L
- Book ID
- 121209591
- Publisher
- Nature Publishing Group
- Year
- 2011
- Tongue
- English
- Weight
- 852 KB
- Volume
- 31
- Category
- Article
- ISSN
- 0950-9232
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## Abstract Nonrandom allelic loss on chromosome 3p is a common event in nasopharyngeal carcinoma (NPC) with the implication that certain tumor suppressor gene(s) in this region are involved in the pathogenesis of these tumors. The __BLU__ gene, located at 3p21.3, has recently been identified as a
## Abstract Chromosome 3p plays an important role in tumorigenesis in many cancers, including nasopharyngeal carcinoma (NPC). We have previously shown chromosome 3p can suppress tumor growth __in vivo__ by using the monochromosome transfer approach, which indicated the chromosome 3p21.3 region was