Anodic acetamidation of adamantane and 1-haloadamantanes

✍ Scribed by Victor R. Koch; Larry L. Miller

• Publisher: Elsevier Science
• Year: 1973
• Tongue: French
• Weight: 171 KB
• Volume: 14
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(00)72436-1

✦ Synopsis

The discovery2a3*4 that large alkaues can be directly oxidized In acetouitrile at a platinum anode provides access to the anodic chemistry of a variety of 8lipbatic compouuds.

In the present Investigation, we have oxidized several adanantyl compounds as an initial step in elucidating this chemistry. This system was chosen because of the availability of 1-ad-tyl derivatives, their low oxidation potential (compared to simpler anrlogs) and the simplicity of the observed chemistry. We report the first product studies of alkane, alkyl chloride and alkyl fluoride oxidations in aprotic media.