Bromination and bridgehead reactivity of 1-aza-adamantane.
โ Scribed by W.N. Speckamp; J. Dijkink; A.W.J.D. Dekkers
- Publisher
- Elsevier Science
- Year
- 1974
- Tongue
- French
- Weight
- 208 KB
- Volume
- 15
- Category
- Article
- ISSN
- 0040-4039
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๐ SIMILAR VOLUMES
Although radical reactions of tertiary amines have been postulated to play an essential role in certain biological processes2 only scarce &endcal information is available3 on this type of reaction. Aiming at novel routes to 3-halogenated 1-aza-adamantanes we have investigated the reaction of la with
A recent investigation of hydrogen abstraction by the trichloromethyl radical from l-substituted adamantanes has been reported by us (1). It was observed that appreciable halogen abstraction by the radical occurred for 1-fluoroadamantane and l-chloroadamantane. Similar halogen abstraction from adama
The direct bromination of adamantane with elemental bromine to give lbromoadamantanel, one of the most versatile intermediates in the derivative n chemistry of adamantaneL, has long been believed to proceed only slowly for no obvious reason, refluxing for three to four hours in neat bromine being th
Qualitatively the orbital scheme given for (2a) in Figure 1 is retained, i.e. AE1,,z4AE2,, is valid for the energy differences AE1,' and AE2,3 between the three highest occupied orbitals. 0 and p' are of the same order. The energy level diagram for the ion (3) should be similar.