Annotation: Fragile X Syndrome: Advances and Controversy
β Scribed by Randi Jenssen Hagerman
- Book ID
- 111116323
- Publisher
- John Wiley and Sons
- Year
- 1992
- Tongue
- English
- Weight
- 906 KB
- Volume
- 33
- Category
- Article
- ISSN
- 0021-9630
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## Abstract Fragile X syndrome, the most common genetic disorder associated with mental retardation is caused by an expansion of the unstable CGG repeat within the __FMR1__ gene. Although overgrowth is not the main hallmark of this condition, the fragile X syndrome is usually included in the differ
Fragile X (FraX) syndrome is the most common cause of inherited mental retardation. The FraX gene (FMR1) has been cloned, and the mutation causing the disease is now known. We estimated the effect of FraX on dental development in 28 affected boys (aged 4.9-17.6 years) and three carrier girls (aged 5