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Current controversies in prenatal diagnosis 1: screening for fragile X syndrome

✍ Scribed by Yaron, Yuval; Musci, Thomas; Cuckle, Howard


Book ID
118765696
Publisher
John Wiley and Sons
Year
2012
Tongue
English
Weight
67 KB
Volume
33
Category
Article
ISSN
0197-3851

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## Objective: The objective of this study was to conduct an economic evaluation of routine prenatal carrier testing for fragile X syndrome. Methods: This economic analysis was conducted from the societal perspective. A cost-benefit equation was developed based on the premise that the cost of routi

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We reviewed the distribution of autosomal fragile sites (FS) and spontaneous chromosome breaks or gaps (CB) at chromosome locations other than those recognized as FS from 100 amniotic fluid samples (AF), 19 chorionic villus samples (CVS), and 5 percutaneous umbilical blood samples (PUBS) referred fo