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Prenatal diagnosis and carrier screening for fragile X by PCR

✍ Scribed by Brown, W. Ted; Nolin, Sarah; Houck, George; Ding, Xiaohua; Glicksman, Anne; Li, Shu-Yun; Stark-Houck, Sandra; Brophy, Patricia; Duncan, Charlotte; Dobkin, Carl; Jenkins, Ed


Publisher
John Wiley and Sons
Year
1996
Tongue
English
Weight
28 KB
Volume
64
Category
Article
ISSN
0148-7299

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The results of 30 prenatal diagnoses for fragile X syndrome are reported. Amniotic fluid cells were examined in 1 case, fetal blood in 4, and chorionic villi samples in the others. Of the 5 fetuses analyzed by cytogenetic methods, 1 had showed 4% of fraXq27.3 expression sites and the pregnancy was t