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Dental maturity is advanced in fragile X syndrome

✍ Scribed by Kotilainen, J.; Pirinen, S.

Publisher
John Wiley and Sons
Year
1999
Tongue
English
Weight
13 KB
Volume
83
Category
Article
ISSN
0148-7299
DOI
10.1002/(sici)1096-8628(19990402)83:4<298::aid-ajmg12>3.0.co;2-4

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✦ Synopsis

Fragile X (FraX) syndrome is the most common cause of inherited mental retardation. The FraX gene (FMR1) has been cloned, and the mutation causing the disease is now known. We estimated the effect of FraX on dental development in 28 affected boys (aged 4.9-17.6 years) and three carrier girls (aged 5.8, 10.4, and 12.7 years). Dental maturity, assessed on the basis of formation [Demirjian A, Goldstein H. 1976:

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