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Angiogenesis Inhibitor Epoxyquinol A: Total Synthesis and Inhibition of Transcription Factor NF-κB

✍ Scribed by Li, Chaomin; Bardhan, Sujata; Pace, Emily A.; Liang, Mei-Chih; Gilmore, Thomas D.; Porco, John A.


Book ID
127016237
Publisher
American Chemical Society
Year
2002
Tongue
English
Weight
118 KB
Volume
4
Category
Article
ISSN
1523-7060

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The synthesis of the recently discovered angiogenesis inhibitors epoxyquinols A and B, having novel polyketide derived dimeric structures, has been accomplished from the readily available Diels-Alder adduct of cyclopentadiene and p-benzoquinone through a short, simple and flexible strategy that is d