Androgen receptor binding activity in human prostate cancer
β Scribed by Ralph C. Benson Jr; David C. Utz; Eileen Holicky; Carlo M. Veneziale
- Publisher
- John Wiley and Sons
- Year
- 1985
- Tongue
- English
- Weight
- 730 KB
- Volume
- 55
- Category
- Article
- ISSN
- 0008-543X
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## Abstract The androgen receptor (AR) is involved in the development and maintenance of the normal prostate and the development and progression of prostate cancer (PCa). Caveolinβ1 (cavβ1) is an AR coβregulator. The expression of this integral membrane protein is upregulated in PCa and correlates
## Abstract Flow diagram of androgen, androgen receptor and caveolinβ1 activity. See Androgen Receptor and Caveolinβ1 in Prostate Cancer by Bennett et al., pp. 961β970.
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## Abstract Endocrine therapy for advanced prostate cancer is based on androgen ablation or blockade of the androgen receptor (AR). AR action in prostate cancer has been investigated in a number of cell lines, their derivatives, and transgenic animals. AR expression is heterogenous in prostate canc
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