Relationship between androgen receptor binding activity in human prostate cancer and clinical response to endocrine therapy
β Scribed by Ralph C. Benson Jr.; Paul A. Gorman; Peter C. O'Brien; Eileen L. Holicky; Carlo M. Veneziale
- Publisher
- John Wiley and Sons
- Year
- 1987
- Tongue
- English
- Weight
- 751 KB
- Volume
- 59
- Category
- Article
- ISSN
- 0008-543X
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
Biopsy material from primary prostatic carcinoma from 25 patients was analyzed with regard to cytosol content of methyltrienolone (a synthetic androgen) binding sites and the receptor content has been correlated to the clinical response to endocrine therapy. A dextran-coated charcoal technique was u
A longstanding goal has been to determine whether androgen receptor (AR) levels could be used to predict the clinical response of metastatic prostate cancer to androgen withdrawal therapy. A major limitation of previous studies was the use of homogenized tissue, which yields an average AR content fo