𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Analytical solution for the linear ideal model of simulated moving bed chromatography

✍ Scribed by Guoming Zhong; Georges Guiochon


Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
869 KB
Volume
51
Category
Article
ISSN
0009-2509

No coin nor oath required. For personal study only.

✦ Synopsis


An analytical solution for linear ideal simulated moving bed (SMB) chromatography is derived. This solution is a set of algebraic equations which allows the calculation of the concentration profiles along the columns and of the concentration histories at the raffinate and extract ports. Using this solution, the operations of SMB under steady-state conditions and during the transition from start-up to steady state are examined. An asymptotic property is found for the steady state. A comparison between SMB and true moving bed (TMB) illustrates their similarities and differences.


πŸ“œ SIMILAR VOLUMES


Scale-up of analytical chromatography to
✍ Gianmarco Zenoni; Francesca Quattrini; Marco Mazzotti; Claudio Fuganti; Massimo πŸ“‚ Article πŸ“… 2002 πŸ› John Wiley and Sons 🌐 English βš– 137 KB

## Abstract The scale‐up of the HPLC separation of the enantiomers of the flavour norterpenoid ketones α‐ionone and α‐damascone from analytical to preparative scale was achieved using the chromatographic simulated moving bed (SMB) technique. Commercial HPLC columns, with heptakis‐(2,3,6‐per‐__O__‐m

Analytical solution to an axial dispersi
✍ Hsin-Tzu Liao; Ching-Yeh Shiau πŸ“‚ Article πŸ“… 2000 πŸ› American Institute of Chemical Engineers 🌐 English βš– 188 KB πŸ‘ 2 views

## Abstract An axial dispersion model for the operation of a fixed‐bed adsorber with a linear adsorption isotherm was formulated and solved analytically using the separation of variables method. The asymptotic solution for a large Peclet number and/or a small operation time was also obtained using

Analytical solution to a model for the s
✍ Yizhou Zheng; Tingyue Gu πŸ“‚ Article πŸ“… 1996 πŸ› Elsevier Science 🌐 English βš– 409 KB

Abstraet--A mathematical model for the startup period of a fixed-bed reactor with first-order reaction kinetics, axial dispersion and film mass transfer resistance was formulated and solved analytically using Laplace transform. The solution can be used to correlate or predict the reactant concentrat

The application of preparative batch HPL
✍ Tony Q. Yan; Carlos Orihuela; David Swanson πŸ“‚ Article πŸ“… 2007 πŸ› John Wiley and Sons 🌐 English βš– 328 KB πŸ‘ 1 views

## Abstract This article discusses the chromatographic resolution of a racemic pharmaceutical intermediate. Preparative batch high performance liquid chromatography (HPLC), supercritical fluid chromatography (SFC), steady‐state recycling (SSR), and simulated moving bed (SMB) were used to resolve a