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Analysis of tropane and related alkaloids

✍ Scribed by Birgit Dräger

Book ID
108339136
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
896 KB
Volume
978
Category
Article
ISSN
1873-3778

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Various tropane alkaloids have been prepared by structural modification of the readily available natural product, scopolamine 1. Reaction of isocyanates with 6,7-dehydrotropine 5 provided a number of urethanes 6a-e. Reductive amination of tropinone 7 and subsequent reaction with isocyanates provided