๐”– Bobbio Scriptorium
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Conformation of Tropane Alkaloids

โœ Scribed by BOSE, AJAY K.; CHAUDHURI, DILIP K. ROY


Book ID
109573171
Publisher
Nature Publishing Group
Year
1953
Tongue
English
Weight
400 KB
Volume
171
Category
Article
ISSN
0028-0836

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Various tropane alkaloids have been prepared by structural modification of the readily available natural product, scopolamine 1. Reaction of isocyanates with 6,7-dehydrotropine 5 provided a number of urethanes 6a-e. Reductive amination of tropinone 7 and subsequent reaction with isocyanates provided

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Recent interest in the conformations of tropane and piperidine derivatives (l-9) prompts us to report our interpretation of the NMR spectra (10) of three tropanes that are substituted in the 2-and 3-positions (11). The