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Ion-exchange HPLC analysis for tropane alkaloids

โœ Scribed by Huen, J. M. ;Thevenin, J. P.


Book ID
102345663
Publisher
John Wiley and Sons
Year
1979
Tongue
English
Weight
74 KB
Volume
2
Category
Article
ISSN
0935-6304

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โœฆ Synopsis


Post-column derivatizationfluorimetric ion-pair technique

Fluorimetric determination of tropane alkaloids in pharmaceuticals


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Pyrrolizidine alkaloid (PA)-containing plants are widely distributed in the world. PAs are hepatotoxic, affecting livestock and humans. PA N-oxides are often present together with PAs in plants and also exhibit hepatotoxicity but with less potency. HPLC-MS is generally used to analyze PA-containing