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Analysis of the surface expression of c-kit and occurrence of the c-kit Asp816Val activating mutation in T cells, B cells, and myelomonocytic cells in patients with mastocytosis

✍ Scribed by Cem Akin; Arnold S Kirshenbaum; Tekli Semere; Alexandra S Worobec; Linda M Scott; Dean D Metcalfe


Book ID
114217449
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
258 KB
Volume
28
Category
Article
ISSN
0301-472X

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Clinical correlates of the presence of t
✍ Alexandra S. Worobec; Tekli Semere; Hiroshi Nagata; Dean D. Metcalfe πŸ“‚ Article πŸ“… 1998 πŸ› John Wiley and Sons 🌐 English βš– 271 KB πŸ‘ 1 views

BACKGROUND. The Asp816Val mutation in the catalytic domain of the c-kit receptor has been identified in patients with systemic mastocytosis. ## METHODS. To determine whether this mutation is associated with identifiable clinical patterns of disease and prognosis, a total of 65 patients with masto