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Cytogenetic abnormalities and their lack of relationship to the Asp816Val c-kit mutation in the pathogenesis of mastocytosis

โœ Scribed by Worobec, Alexandra S.; Akin, Cem; Scott, Linda M.; Metcalfe, Dean D.


Book ID
119496767
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
13 KB
Volume
102
Category
Article
ISSN
1097-6825

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Clinical correlates of the presence of t
โœ Alexandra S. Worobec; Tekli Semere; Hiroshi Nagata; Dean D. Metcalfe ๐Ÿ“‚ Article ๐Ÿ“… 1998 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 271 KB ๐Ÿ‘ 1 views

BACKGROUND. The Asp816Val mutation in the catalytic domain of the c-kit receptor has been identified in patients with systemic mastocytosis. ## METHODS. To determine whether this mutation is associated with identifiable clinical patterns of disease and prognosis, a total of 65 patients with masto