Amplification of the beta-globin gene by the polymerase chain reaction (PCR) and direct sequencing were used for a fast and reliable identification of the beta-globin variant Hb D Los Angeles and revealed the predicted G----C substitution in codon 121. The same method showed the molecular defect in
✦ LIBER ✦
Analysis of the Hb M Milwaukee mutation at the DNA level
✍ Scribed by J. Horst; R. Schäfer; E. Kleihauer; E. Kohne
- Book ID
- 114710072
- Publisher
- John Wiley and Sons
- Year
- 1983
- Tongue
- English
- Weight
- 512 KB
- Volume
- 54
- Category
- Article
- ISSN
- 0007-1048
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