✍ Scribed by C.E. Morreal; T.L. Dao; A.J. Spiess
No coin nor oath required. For personal study only.
Column chromatography and electron-capture gas chromatography have been applied to the separation and quantitative analysis of the K-region epoxide of 7,12-dimethylbenz(a)anthracene, S-hydroxy-7,12-dimethylbenz(a)anthracene, and trans-5,6-dihydro-5,6-dihydroxy-7,12-dimethylbenz(a)anthracene.
Deactivation of chromatographic alumina with water permitted quantitative elution of the three compounds. In a solution of acetone and water, the epoxide was hydrolyzed to the 5,6-diol, but none of the 5-hydroxy derivative was formed.
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