Analysis of RET proto-oncogene abnormalities in patients with MEN 2A, MEN 2B, familial or sporadic medullary thyroid carcinoma
โ Scribed by Chiefari, E.; Russo, D.; Giuffrida, D.; Zampa, G. A.; Meringolo, D.; Arturi, F.; Chiodini, I.; Bianchi, D.; Attard, M.; Trischitta, V.; Bruno, R.; Giannasio, P.; Pontecorvi, A.; Filetti, Sebastiano
- Book ID
- 125337727
- Publisher
- Springer-Verlag
- Year
- 1998
- Tongue
- English
- Weight
- 763 KB
- Volume
- 21
- Category
- Article
- ISSN
- 0391-4097
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
Duchenne muscular dystrophy (DMD) is an X-linked degenerative disorder of muscle, caused by gross rearrangements by the dystrophin gene in two-thirds of cases. The remaining one-third of patients may carry more subtle mutations that are difficult to detect because of the large size and complexity of
Communicated by B w e A.J. Pondei Multiple endocrine neoplasia type 2 [MEN 21 is an autosomal dominant cancer syndrome with two subtypes, 2A and 2B. MEN 2A and medullary thyroid cancer [MTC] are caused by >25 different point mutations in exons 10, 11, and 13 of the RET proto-oncogene, whereas MEN 2B