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Analysis of ras oncogene mutations in human squamous cell carcinoma of the head and neck

✍ Scribed by F. Nuñez; O. Dominguez; E. Coto; C. Suarez-Nieto; P. Perez; C. Lopez-Larrea


Book ID
113404059
Publisher
Elsevier Science
Year
1992
Tongue
English
Weight
692 KB
Volume
1
Category
Article
ISSN
0960-7404

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## Loss of heterozygosity (LOH ) at chromosome band 10q23 occurs frequently in a wide variety of human tumors. A recently identified candidate tumor suppressor gene, PTEN located on 10q23, is mutated in multiple advanced cancers. To explore whether PTEN is associated with human squamous cell carci