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Analysis of Rad3 and Chk1 protein kinases defines different checkpoint responses

✍ Scribed by Martinho, R. G.


Book ID
111745800
Publisher
Nature Publishing Group
Year
1998
Tongue
English
Weight
702 KB
Volume
17
Category
Article
ISSN
0261-4189

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## Abstract In response to certain types of DNA damage, ataxia telangiectasia and rad3‐related (ATR) phosphorylates checkpoint kinase 1 (CHEK1) resulting in cell cycle arrest and subsequent DNA repair. __ATR__ and __CHEK1__ contain mononucleotide microsatellite repeat regions, which are mutational