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Ultrasound activates ataxia telangiectasia mutated- and rad3-related (ATR)-checkpoint kinase 1 (Chk1) pathway in human leukemia Jurkat cells

✍ Scribed by Furusawa, Yukihiro; Iizumi, Takashi; Fujiwara, Yoshisada; Hassan, Mariame Ali; Tabuchi, Yoshiaki; Nomura, Takaharu; Kondo, Takashi

Book ID: 118502771
Publisher: Elsevier Science
Year: 2012
Tongue: English
Weight: 615 KB
Volume: 19
Category: Article
ISSN: 1350-4177
DOI: 10.1016/j.ultsonch.2012.04.003

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## Abstract In response to certain types of DNA damage, ataxia telangiectasia and rad3‐related (ATR) phosphorylates checkpoint kinase 1 (CHEK1) resulting in cell cycle arrest and subsequent DNA repair. __ATR__ and __CHEK1__ contain mononucleotide microsatellite repeat regions, which are mutational