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Analysis of point mutations in HPRT mutant T-lymphocytes derived from coke-oven workers

✍ Scribed by Maddalena Mognato; Marta Graziani; Lucia Celotti


Book ID
114072616
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
173 KB
Volume
431
Category
Article
ISSN
0027-5107

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nine resistant T-lymphocytes were isolated from two blood samples obtained 4 months apart from a 50year-old male subiect. Sixty-six of these mutants were characterized at the DNA sequence level using cDNA. One particular single base substitution was recovered a total of 23 fimes. The majority of T-c