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Determination of HPRT mutant frequency and molecular analysis of T-lymphocyte mutants derived from coke-oven workers

✍ Scribed by Nicola Zanesi; Maddalena Mognato; Massimo Pizzato; Cristina Viezzer; Giovanni Ferri; Lucia Celotti


Book ID
117767553
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
133 KB
Volume
412
Category
Article
ISSN
1383-5718

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nine resistant T-lymphocytes were isolated from two blood samples obtained 4 months apart from a 50year-old male subiect. Sixty-six of these mutants were characterized at the DNA sequence level using cDNA. One particular single base substitution was recovered a total of 23 fimes. The majority of T-c