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Analysis of mutations in the Pig-a gene of spleen T-cells from N-ethyl-N-nitrosourea-treated fisher 344 rats

โœ Scribed by Daishiro Miura; Joseph G. Shaddock; Roberta A. Mittelstaedt; Vasily N. Dobrovolsky; Takafumi Kimoto; Yoshinori Kasahara; Robert H. Heflich

Publisher
John Wiley and Sons
Year
2011
Tongue
English
Weight
92 KB
Volume
52
Category
Article
ISSN
0893-6692

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Development of an in vivo gene mutation assay using the endogenous Pig-A gene: II. Selection of Pig-A mutant rat spleen T-cells with proaerolysin and sequencing Pig-A cDNA from the mutants
โœ Daishiro Miura; Vasily N. Dobrovolsky; Roberta A. Mittelstaedt; Yoshinori Kasaha ๐Ÿ“‚ Article ๐Ÿ“… 2008 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 365 KB ๐Ÿ‘ 1 views

## Abstract We previously reported that rat spleen Tโ€cells and peripheral red blood cells that are deficient in glycosylphosphatidylinositol (GPI) synthesis [presumed mutants for the phosphatidylinositol glycan complementation group A gene (__Pigโ€A__)] could be detected by flow cytometry (FCM) as c