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Analysis of mixtures of hydrophilic peptides by continuous-flow fast atom bombardment mass spectrometry

โœ Scribed by Richard M. Caprioli; William T. Moore; Gordon Petrie; Kenneth Wilson


Publisher
Elsevier Science
Year
1988
Tongue
English
Weight
759 KB
Volume
86
Category
Article
ISSN
0168-1176

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## Combined capillary zone electrophoresis (CZE)-continuous-flow fast atom bombardment (CF-FAB) mass spectrometry is described for the analysis of mixtures of peptides. A 90 cm x 50 pm I.D. fused-silica capillary column was used for electrophoretic separations and was connected to the CF-FAB probe

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Conventional positive fast atom bombardment (FAB) and continuous-flow FAB analysis were carried out with permethylated lacto-N-tetraose. This latter method, a new approach, has been used to analyze a mixture of permethylated oligosaccharides by liquid chromatography-mass spectrometry (LC-MS) with a