Analysis of mitochondrial DNA somatic mutations in OXYS and Wistar strain rats
β Scribed by U. N. Rotskaya; I. B. Rogozin; E. A. Vasyunina; N. G. Kolosova; B. A. Malyarchuk; G. A. Nevinsky; O. I. Sinitsyna
- Book ID
- 110155155
- Publisher
- Springer
- Year
- 2009
- Tongue
- English
- Weight
- 239 KB
- Volume
- 74
- Category
- Article
- ISSN
- 0006-2979
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract Exciting new studies are increasingly strengthening the link between mitochondrial mutagenesis and tumor progression. Here we provide a comprehensive review and metaβanalysis of studies reporting on mitochondrial DNA mutations in common human cancers. We discuss possible mechanisms by w
## Abstract Recent studies of various cancers, such as those of the breast, head and neck, bladder and lung, reported that 46β64% of somatic mutations in the Dβloop region of mitochondrial DNA (mtDNA) are observed. However, in esophageal cancer, only a low rate (5%) of somatic mutations has so far
Chloroplast and mitochondrial DNAs have been examined by comparison of restriction enzyme patterns in asymmetric hybrid plants, resulting from the fusion between leaf mesophyll protoplasts of Nicotiana tabacum (Solanaceae), and irradiated cell culture protoplasts of Daucus carota (Umbellifereae). Th
## Abstract Mitochondrial DNA (mtDNA) has been proposed to be involved in carcinogenesis because of its high susceptibility to oxidative DNA damage and limited repair mechanisms. For investigation of the potential role of somatic mtDNA mutations in the tumorigenesis of oral cancer, we screened the