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Associations between hyperglycaemia and somatic transversion mutations in mitochondrial DNA of people with diabetes mellitus

✍ Scribed by J. Kamiya; Y. Aoki


Publisher
Springer
Year
2003
Tongue
English
Weight
227 KB
Volume
46
Category
Article
ISSN
0012-186X

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Heteroplasmy levels of a mitochondrial g
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We showed previously that a mutation in the mitochondria1 tRNAL"(UUR' gene at position 3243 associates with maternally inherited diabetes and deafness (MIDD). This mutation shows heteroplasmy in DNA from peripheral blood and other tissues. To examine whether heteroplasmy levels in peripheral blood D