Analysis of biopolymers by matrix-assisted laser desorption/ionization (MALDI) mass spectrometry
β Scribed by U. Bahr; M. Karas; F. Hillenkamp
- Book ID
- 112625145
- Publisher
- Springer
- Year
- 1994
- Tongue
- English
- Weight
- 862 KB
- Volume
- 348
- Category
- Article
- ISSN
- 1618-2650
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A new method of liquid sample introduction for a time-of-flight mass spectrometer (TOF-MS) has been developed by applying the method of matrix-assisted laser desorption ionization to aerosols. Analyte biomolecules are dissolved in a methanol solvent along with a UVabsorbing matrix and formed into an
Quantitative aspects of oligonucleotide analysis by matrix-assisted laser desorption/iotion (MALDI) mass spectrometry remain largely unexplored relative to the efforts that have been devoted to quantitative peptide and protein analysis. The successful quantitation of these other biopolymers coupled