Analogs of the Aminonucleoside Derived from Puromycin. The Synthesis of 3'-Amino-3'-deoxyguanosine and 3'-Amino-3'-deoxycrotonoside
β Scribed by Kissman, Henry M.; Small Hoffman, Arlene; Weiss, Martin J.
- Book ID
- 126241985
- Publisher
- American Chemical Society
- Year
- 1963
- Tongue
- English
- Weight
- 413 KB
- Volume
- 6
- Category
- Article
- ISSN
- 0022-2623
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## Abstract 3β²βAminoβ3β²βdeoxyguanosine was synthesized from guanosine in eight steps and 58% overall yield. The 2β²,3β²βdiol of 5β²β__O__β[(__tert__βbutyl)diphenylsilyl]β2β__N__β[(dimethylamino)methylidene]guanosine was reacted with __Ξ±__βacetoxyisobutyryl bromide and treated with 0.5n NH~3~ in MeOH t
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