✦ LIBER ✦

An uncommon morphological variant of acute promyelocytic leukemia

✍ Scribed by Elizabeth Jacob; Amita Ranger; Mamta Sohal; Barbara J. Bain

Publisher: John Wiley and Sons
Year: 2011
Tongue: English
Weight: 438 KB
Volume: 87
Category: Article
ISSN: 0361-8609
DOI: 10.1002/ajh.22129

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Morphologic heterogeneity of acute promy

Morphologic heterogeneity of acute promyelocytic leukemia: Therapy-related acute promyelocytic leukemia presenting with FAB-M2 morphology

✍ S. Sinha; L. Aish; T.H. Oo 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 285 KB 👁 1 views

To the Editor: Translocation t(9;22)(q34;q11) is found in 1-2% of newly diagnosed patients with de novo AML. The prognosis of Ph þ AML is very poor with a median survival time of only 7 months. We present two patients with de novo Ph þ AML who received induction chemotherapy and post-remission imati

Morphologic and cytochemical characteris

Morphologic and cytochemical characteristics of acute promyelocytic leukemia

✍ F. R. Davey; R. B. Davis; J. M. Maccallum; D. A. Nelson; R. J. Mayer; E. D. Ball 📂 Article 📅 1989 🏛 John Wiley and Sons 🌐 English ⚖ 1017 KB

The existence of two distinct subtypes of acute promyelocytic leukemia was confirmed and characterized based on morphologic features of leukemic cells in a series of 63 patients studied by the Cancer and Leukemia Group B (CALGB). Seventeen patients (27%) had microgranular leukemic cells (M3V), and 4

Molecular analysis of simple variant tra

Molecular analysis of simple variant translocations in acute promyelocytic leukemia

✍ Julian Borrow; Kathy Howe; Audrey Goddard; Dr. Ellen Solomon; Janet Shipley; Fio 📂 Article 📅 1994 🏛 John Wiley and Sons 🌐 English ⚖ 832 KB

The primary cytogenetic abnormality in acute promyelocytic leukemia (APL; FAB M3) is a reciprocal translocation, t( 15; I7)(q22;q I2), which serves t o fuse the PML gene on chromosome I5 t o the retinoic acid receptor alpha (RAM) gene on chromosome 17. A PML-MM fusion message transcribed from the de

A Variant Form of Acute Promyelocytic Le

A Variant Form of Acute Promyelocytic Leukemia With Marked Myelofibrosis

✍ Kenji Fukuno; Hisashi Tsurumi; Takeshi Yoshikawa; Toshiki Yamada; Masami Oyama; 📂 Article 📅 2001 🏛 Carden Jennings Publishing 🌐 English ⚖ 92 KB

Morphology of acute promyelocytic leukem

Morphology of acute promyelocytic leukemia with cytogenetic or molecular evidence for the diagnosis: Characterization of additional microgranular variants

✍ Neame, Peter B.; Soamboonsrup, Praniti; Leber, Brian; Carter, Ronald F.; Sunislo 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 472 KB 👁 2 views

Early diagnosis of t(15;17) acute promyelocytic leukemia (APL) is essential because of the associated disseminated intravascular coagulation and the unique response of the disease to all-trans retinoic acid (ATRA) therapy. Early diagnosis depends primarily on morphological recognition. The French-Am

Acute promyelocytic leukemia (APL) with

Acute promyelocytic leukemia (APL) with an unusual cytogenetic presentation

✍ Yorulmazoglu, Erol; Gezer, Sefer; Gregory, Stephanie A.; Hsu, Wei-Tong 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 29 KB 👁 2 views

We present a patient with APL because of the therapeutic implications of the singular chromosomal rearrangement present in his leukemic cells. Our patient is a 60-year-old male who presented with easy bruisability, gum bleeding, weakness, decreased appetite, and night sweats. He is a retired admiral