𝔖 Bobbio Scriptorium
✦   LIBER   ✦

An ortho­rhom­bic polymorph of palonosetron hydro­chloride

✍ Scribed by Ravikumar, Krishnan ;Sridhar, Balasubramanian

Publisher
International Union of Crystallography
Year
2007
Tongue
English
Weight
351 KB
Volume
63
Category
Article
ISSN
1600-5368

No coin nor oath required. For personal study only.

✦ Synopsis

A new polymorph of the title compound {systematic name: 2-[(S)-1-azoniabicyclo[2.2.2]oct-3-yl]-2,3,3a,4,5,6-hexahydro-1__H__-benz[de]isoquinolin-1-one chloride}, C~19~H~25~ON~2~
^+^·Cl^−^, an anti-emetic and antinausea agent, has been obtained by crystallization from dimethylformamide. In the orthorhombic polymorph reported here, molecules are arranged into polar (001) layers, with adjacent layers in an antiparallel arrangement, whereas in the earlier reported monoclinic form, adjacent layers are arranged in a parallel manner.

📜 SIMILAR VOLUMES

Malonamide: an ortho­rhom­bic polymorph
Malonamide: an ortho­rhom­bic polymorph
✍ Nichol, Gary S. ;Clegg, William 📂 Article 📅 2005 🏛 International Union of Crystallography 🌐 English ⚖ 237 KB

An orthorhombic polymorph of malonamide, C 3 H 6 N 2 O 2 , is reported. The unit-cell dimensions, crystallographic symmetry and some aspects of the molecular geometry are significantly different from those of the known monoclinic form [Chieh et al. (1970). J. Chem. Soc. A, pp. 179-184] and of the te

An ortho­rhom­bic polymorph of myo-inosi
An ortho­rhom­bic polymorph of myo-inositol
✍ Khan, Uzma ;Qureshi, Rizwana A. ;Saeed, Sadaf ;Bond, Andrew D. 📂 Article 📅 2007 🏛 International Union of Crystallography 🌐 English ⚖ 116 KB

The title compound, C 6 H 12 O 6 , has been obtained from the ethanol fraction of the aerial part of the plant Incarvillea emodi (Wall. ex Royle) Chatterjee, after recrystallization from ethanol/ethyl acetate (60:40). Each molecule is involved in 12 hydrogen bonds, as has been found in other reporte