An Optimized in situ Procedure for the Oxazaborolidine Catalyzed Enantioselective Reduction of Prochiral Ketones. -The catalyst prepared from (S)-diphenyl prolinol is found to be the best amongst several other analogues for the reduction of alkyl aryl ketones. -(PRASAD, K. R.
An optimised in situ procedure for the oxazaborolidine catalysed enantioselective reduction of prochiral ketones
โ Scribed by K.R.K. Prasad; N.N. Joshi
- Publisher
- Elsevier Science
- Year
- 1996
- Tongue
- English
- Weight
- 263 KB
- Volume
- 7
- Category
- Article
- ISSN
- 0957-4166
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## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Several conformationally constrained oxazaborolidine catalysts have been evaluated in the reduction of ketone 1. Readily accessible (1R, 2S ) l-amino-2 .tetralol (B-H) derived oxazaborolidine catalyst (6b) proves to be the most effective and practical catalyst in the reduction of bromo-ketone I (96%
## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.