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An involvement of mitogen-activated protein kinase pathway in mechanism of antidepressant drug action

✍ Scribed by Detka, Jan; Szczęsny, Ewa; Szymańska, Magdalena; Leśkiewicz, Monika; Basta-Kaim, Agnieszka; Kubera, Marta; Jantas, Danuta; Regulska, Magdalena; Budziszewska, Bogusława; Grygier, Beata; Lasoń, Władystaw

Book ID: 122219906
Publisher: Elsevier
Year: 2010
Tongue: English
Weight: 62 KB
Volume: 62
Category: Article
ISSN: 1734-1140
DOI: 10.1016/S1734-1140(10)71134-8

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## Abstract ## BACKGROUND The mitogen‐activated protein kinase (MAPK) cascade is activated in response to various extracellular stimuli. The authors investigated the involvement of the p38 MAPK, a member of the MAPK superfamily, cascade in hepatoma cell lines and in human hepatocellular carcinoma